Presentation and management of syndromic and non-syndromic patients with multiple odontogenic keratocysts

This case series reports the clinical presentation and management of multiple odontogenic keratocysts (OKCs) in patients with Gorlin Goltz syndrome non-syndromic patients. Eight presented features keratocyst at department Oral Maxillofacial Surgery. The diagnosis was confirmed following clinical, radiographic histopathological examination. Initially OKC on an incisional biopsy. Major minor criteria were followed for syndrome. Smaller cysts all enucleated larger marsupialization planned either alone or by enucleation. Patients 1 month, 3 months, 6 months yearly interval to check bone healing recurrences. Association identified four whom males age range 12–37 years. Among that had OKCs, three female one male 09–50 years; two familial OKCs. In syndromic patients, recognized manifestations variable frequency: calcification falx cerebri chest deformity (100%); macrocephaly frontal bossing hypertelorism (75%); basal cell carcinoma (25%); pectus flame shaped hands feet (25%) syndactyly (50%). Palmar plantar pits, cleft lip palate, ovarian fibroma medulloblastoma not any patient. OKCs mandible more commonly involved than maxilla. should be evaluated thoroughly carcinomatous lesions ruled out. Meticulous follow up is vital as associated malignancies may first manifestation this Given fact have higher rate recurrence isolated long term warranted.